Chenxiong Le Selected Research

sifalimumab

1/2014	A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients.
11/2011	Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study.
3/2010	A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis.

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Chenxiong Le Research Topics

Disease

2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 01/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Clostridium Infections 01/2019
1	Infections 01/2019
1	Polymyositis 01/2014
1	Dermatomyositis (Dermatopolymyositis) 01/2014
1	Myositis (Idiopathic Inflammatory Myopathies) 01/2014
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2011
1	Asthma (Bronchial Asthma) 02/2011
1	Myocardial Infarction 03/2010
1	Psoriasis (Pustulosis Palmaris et Plantaris) 03/2010

Drug/Important Bio-Agent (IBA)

4	Monoclonal AntibodiesIBA 01/2014 - 03/2010
3	sifalimumabIBA 01/2014 - 03/2010
2	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2020 - 01/2019
2	Pharmaceutical PreparationsIBA 01/2014 - 03/2010
1	LactamsIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	Interferon Type IIBA 11/2011
1	InterferonsIBA 11/2011
1	enokizumabIBA 02/2011
1	Interferon-alpha (Interferon Alfa)IBA 03/2010

Therapy/Procedure

1	Aftercare (After-Treatment) 01/2019